Results in For Potential MS Therapies

  • In a two-year Phase III trial, the oral MS therapy BG-12 significantly reduced – by up to 51%-the average number of annual MS relapses.  More than 1,400 people with relapsing-remitting MS participated in the study.  BG-12 is thought to inhibit the immunce cells and molecules that are involved in MS attacks on the brain and spinal cord.  This study should help to define further the safety and promise of BG-12 as a potential therapy for relapsing MS.
  • The experimental intravenous MS therapy alemtuzumab significantly reduced relapse rates and the worsening of disability in a two-year Phase III study that compared alemtuzumab to Rebif.  The study, called CARE-MS II, involved 840 people with relapsing-remitting MS.  The FDA has fast-tracked alerntuzumab, which should speed up future review.
  • A study of 324 patients comparing the MS oral therapy teriflunomide with Rebif found no significant difference in the numbers of participants in each group who experienced events defined as treatment failure.  Teriflunomide is thought to prevent damage to the nervous system by immune cells.  A previous phase III trial was more successful and three others are ongoing.  The FDA is reviewing an application for marketing approval of teriflunomide.

To stay current on MS therapies in the pipeline for FDA approval, sign up for MS eNEWS at

Source: Northern California MS Connection

2 comments on “Results in For Potential MS Therapies

  1. Pingback: Study Confirms Efficacy of Oral Fumarate in Multiple Sclerosis « Alternative Holistic Health Answers

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